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Ketamine affects everyone differently, based on: size, weight and health whether the person is used to taking it whether other drugs are taken around the same time the amount taken the strength of the drug (varies from batch to batch) The following effects may be experienced: feeling happy and relaxed feeling detached from your body lowered sensitivity to pain visual and auditory hallucinations confusion and clumsiness increased heart rate and blood pressure drowsiness slurred speech and blurred vision anxiety and panic vomiting