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The Crew-10 mission will be the first spaceflight for Nichole Ayers, who is a major in the U.S. Air Force and the first member of NASA’s 2021 astronaut class named to a crew. Ayers served as an instructor pilot and mission commander in the T-38 ADAIR and F-22 Raptor, leading multinational and multiservice missions worldwide. She has more than 1,400 total flight hours, including more than 200 in combat. Ayers was born in San Diego, California, but currently lives in Colorado Springs with her husband.