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7-Hydroxymitragynine (7-OH) is a potent terpenoid indole alkaloid derived from the kratom plant (Mitragyna speciosa) or produced as an active metabolite of mitragynine. It acts as a powerful -opioid receptor agonist, exhibiting significant, fast-acting pain relief—up to 13 times more potent than morphine in some tests. Due to its high addiction potential and unregulated, rapid growth in popularity, 7-OH is frequently sold in concentrated forms at smoke shops.